WOMBAT Newsletter
    January 2008


Welcome to the January 2008 issue.

In this issue:


WOMBAT WORKSHOPS 

March 2008

Women's and babies health and wellbeing - improving outcomes.

Saturday 15th March. Agnes Walsh House, King Edward Memorial Hospital, Subiaco, WA 

Participants will focus on an important question in maternal or perinatal healthcare. Working in small groups they will examine how this question could be addressed using the clinical trial research framework. The workshop will cover important issues in the design and conduct of clinical trials. Including: getting the question right, determining the sample size and ethical considerations.

Contact Claire Parker: 08 9340 1369 or email: cparker@obsgyn.uwa.edu.au

or Rebecca Tooher: 08 8161 7660 or email: rebecca.tooher@adelaide.edu.au  for registration (essential).

April 2008

Designing a protocol for a maternal or perinatal RCT.

Friday April 18 and Saturday morning April 19.

Education Centre, Gold Coast Hospital, Little High Street, Southport

For more information, please go to http://www.wombatcollaboration.net/conferences  or contact Rebecca Tooher: rebecca.tooher@adelaide.edu.au or phone +61 8 8161 7660


Other workshops, meetings and conferences relevant to maternal and perinatal health 

IMPACT WORKSHOP: Saturday April 19th (pm) and Sunday 20th (am)

Education Centre, Gold Coast Hospital, Little High Street, Southport 

4 Sessions:  

1 & 2: Presentations of trials in the planning stages and trials currently recruiting requiring new centres and/or recruits;

3: Presentations of trials in the planning stage;

4: Guideline development and getting research into practice. 

CALL FOR ABSTRACTS: CLOSING DATE FOR SUBMISSION: 8 FEB 2008 

For further information about the IMPACT Workshop contact Jonathon Morris (IMPSCT Committee Chair) jmorris@med.usyd.edu.au or Kate Levett klevett@med.usyd.edu.au

Registration forms are available on the website: http://www.psanzimpact.org  

PSANZ Perinatal Mortality Group (PMG) meeting and Australia & New Zealand Stillbirth Alliance (ANZSA) WORKSHOP April 18 and 19. Getting Guidelines Into Practice: Using The PSANZ Perinatal Mortality Audit Guidelines Effectively.

Education Centre, Gold Coast Hospital, Little High Street, Southport. For more information, please go to http://www.psanzpnmsig.org/  or contact Vicki Flenady: Vicki.Flenady@mater.org.au  or Anais Gschwind: anais.gschwind@mater.org.au  

Cochrane Work-in: Sunday April 20 (pm)
Education Centre, Gold Coast Hospital, Little High Street, Southport

The work-in provides and opportunity for Cochrane authors to progress their Cochrane review titles, protocols, and reviews with the support of experienced reviewers.

For further details please contact Philippa Middleton: philippa.middleton@adelaide.edu.au or Phone: 08 8161 7612 

Australian College Neonatal Nurses Association Inc Annual Conference “Nurturing Generation Z” April 19 – 20. For further information, please go to: www.acnn.org.au 

Perinatal Society of Australia and New Zealand Annual Congress “Celebrating 25 years: Reflections and Projections” April 20 – 23. For more information: www.psanz08.eventplanners.com.au
14th Conference of the International Society for Research in Human Milk and Lactation (ISRHML). Jan 31–Feb 5, Perth. For more information, please go to http://www.isrhml.org.umu.se
Australasian Cochrane Symposium 22 - 23 May 2008, Hobart.
Each year the Australasian Cochrane Centre hosts a meeting for Australasian contributors to the Cochrane Collaboration. This year, we will be hosting a Symposium for Australasian review authors in Hobart. http://www.cochrane.org.au 
28th International Confederation of Midwives (ICM) Triennial Congress 1-5 June in Glasgow, UK. For further information: www.midwives2008.org  
Perinatal Medicine 2008 June 2-4 Harrogate, UK.

Early Bird registration on or before: 28th February 2008. Further information: http://www.perinatalmedicine2008.ukevents.org/default.htm 

Fetal and Neonatal Physiological Society 35th Annual Meeting

June 22–25. Netherlands. For more information:  http://www.fnps-society.org


Other related conferences and meetings

Involving People in Research Symposium March 5 – 6 in Perth. For more information, please go to: www.sph.uwa.edu.au/go/sph/involvingpeopleinresearch

General Practice & Primary Health Care Research Conference 4-6 June in Hobart. Abstracts close 22 Feb 2008. See website for further details: www.phcris.org.au/conference/2008/?promoid=131 


What’s new on the WOMBAT website? 

The list of all the Maternal and Neonatal RCTs for Australian centres has recently been updated and can be found under the heading PERINATAL TRIALS on the WOMBAT homepage www.wombatcollaboration.net. All the trials are listed according to their current status and are grouped under a classification of Maternal or Neonatal RCTs. Please let us know if your trial is not listed or if the information provided is not accurate. 

Under RESOURCES FOR TRIALLISTS on the homepage, there is a section called Maternal and Perinatal Trial Toolkits. These Toolkits include a range of topics, including: 

We welcome feedback on new Toolkits and suggestions for improving the existing Toolkits. Please contact the WOMBAT Education Officer, Rebecca Tooher by email: r.tooher@wombatcollaboration.net 


Trials requiring more centres & more recruits:

BOOST II: Benefits of Oxygen Saturation Targeting Study

If you would like more information on becoming involved in this trial: visit perinatal trials page or email boost2@ctc.usyd.edu.au

PROGRESS Trial: Progesterone after previous preterm birth for the prevention of neonatal respiratory distress syndrome

If you would like more information on becoming involved in this trial: visit perinatal trials page or email progress@adelaide.edu.au

PPROMT Trial: Preterm Pre-Labour Rupture of Membranes Close to Term Trial
If you would like more information on becoming involved in this trial: visit perinatal trials page or email ppromt@med.usyd.edu.au

TWINS: Timing of Birth at Term – a randomised controlled trial (ACTOBAT)
If you would like more information on becoming involved in this trial visit perinatal trials page or http://www.health.adelaide.edu.au/og/research/mpctu.html or email twins@adelaide.edu.au


Trial News

Congratulations to all those involved in the PPROMPT RCT. They exceeded their end of year target of 300 and have achieved 322 recruits by 17 January 2008.


New Australian and perinatal trials (or newly registered trials)

Not yet recruiting
A double-blind randomised controlled trial of oxytocin bolus plus placebo infusion versus oxytocin bolus plus oxytocin infusion for the prevention of uterine atony and post partum haemorrhage at elective caesarean section  ACTRN12607000631404
Self-management versus usual care for the treatment of mastitis following childbirth ACTRN12607000438459
Cooling for perineal pain relief after childbirth: randomised trial ACTRN12607000557437
Dural puncture in labour: Intrathecal catheter versus epidural (The ICE Pilot Study) to prevent the need for epidural blood patch ACTRN12608000009314
A randomized, double-Blinded, sham-controlled study to evaluate the anti-emetic efficacy of the pressure right acupressure wristband versus placebo wristbands ACTRN12607000585426 
Follow-up complete
Randomised trial of dopamine vs dobutamine for treatment of low systemic blood flow in very preterm infants ACTRN12607000152426  

New publications of Australian perinatal trials

Maternal

Perineal Outcomes and Maternal Comfort Related to the Application of Perineal Warm Packs in the Second Stage of Labor: A Randomized Controlled Trial. Dahlen HG, Homer CSE, Cooke M, Upton A, Nunn R, Brodrick B.Birth 2007;34 (4):282-290. 

Managing back pain in pregnancy using a support garment: a randomised trial. Kalus SM, Kornman LH, Quinlivan JA. BJOG 2008;115:68-75. 

Use of a decision aid for prenatal testing of fetal abnormalities to improve women's informed decision making: a cluster randomised controlled trial [ISRCTN22532458]. Nagle C, Gunn J, Bell R, Lewis S, Meiser B, Metcalfe S, Ukoumunne OC, Halliday J. BJOG 2008;115:339-47

Neonatal

Long-term effects of caffeine therapy for apnea of prematurity. Schmidt B, Roberts RS, Davis P, Doyle LW, Barrington KJ, Ohlsson A, Solimano A, Tin W; Caffeine for Apnea of Prematurity Trial Group. N Engl J Med 2007;357(19):1893-1902. 

Outcomes at 2 years of age after repeat doses of antenatal corticosteroids. Crowther CA Doyle LW, Haslam RR, Hiller JE, Harding JE, Robinson JS; ACTORDS Study Group. N Engl J Med 2007;357(12):1179-1189.


Recent publications of interest

Neonatal

Kirpalani H, Barks J, Thorlund K, Guyatt G. Cooling for neonatal hypoxic ischemic encephalopathy: do we have the answer? Pediatrics 2007;120:1126-30

Methodological paper of interest

Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials. Pildal J, Hróbjartsson A, Jørgensen KJ, Hilden J, Altman DG, Gøtzsche PC. Int J Epidemiol. 2007;36(4):847-57.


Health Knowledge Network

Health Knowledge Network (HKN) is a knowledge transfer service of the Cochrane Consumers and Communication Review Group, La Trobe University. Visit the new HKN pages for resources and information or register to receive monthly email Evidence and Resource bulletins.

HKN website: http://www.latrobe.edu.au/cochrane/HKN/HKNindex.html

Helen Dilkes email: hkn@latrobe.edu.au


Further Information

For more information on WOMBAT initiatives, please contact the WOMBAT Collaboration national co-ordinator: p.middleton@WOMBATcollaboration.net

The WOMBAT Collaboration is funded through a NHMRC enabling grant.