WOMBAT Newsletter
    September 2007


Welcome to the September issue of WOMBAT News. This monthly update will be a regular source of important information on WOMBAT workshops, events and other news.

In this issue:


WOMBAT Meetings / Workshops:

Further information available on the WOMBAT website Conferences page

November 2007, Brisbane
Mater Research Support Centre and Centre for Clinical Studies, Mater Health Services Brisbane in collaboration with WOMBAT: Evidence Based Health Care Course
November 23 & 24: Evidence Based Health Care Course
Mater Children’s Hospital

For programme and registration information email: Sharon.Egan@mater.org.au

ADVANCE NOTICE
April 2008, Gold Coast
WOMBAT meeting; IMPACT Network meeting; Perinatal Mortality meeting
Venue: TBA
April 18 – 20

Other Meetings / Workshops:

October 2007, London
ISA 2007: 3rd Annual conference of the International Stillbirth Alliance
October 1-4

For programme information and registration details: http://www.isa2007.org/

October 2007, Gold Coast
RANZCOG
October 2-5

For programme information and registration details: www.ranzcog2007asm.com.au

October 2007, Brisbane

Mater Research Support Centre and Centre for Clinical Studies, Mater Health Services Brisbane October 06 & 13: Statistics for Clinical Research: an Introductory Course
For information and registration details, please contact Kristen by phone: (07) 3163 1587 or email: Kristen.Gilshenan@mater.org.au

October 2007, Melbourne
National Research Ethics Conference
October 16-18

The Conference seeks to promote debate about the ethical dimensions of human research. Good research is ethical in design as well as in conduct.

This conference provides an additional opportunity to provide information about the new National Statement. The National Ethics Application Form is being revised to take account of the new National Statement, and will be available before the end of 2007.

For programme information and registration details: http://www.nhmrc.gov.au/ethics/conference.htm

November 2007, Perth
5th International Congress on Developmental Origins of Health & Disease (DOHAD)
November 6 - 10

DOHaD is emerging as one of the most significant forms of international research in determining the prevention and treatment of many child and adult illnesses. This year, there will be a strong emphasis on the political and economic implications for emerging nations.

By attending, you will gain access to some of the highest quality research currently in progress.

For further information and registration details go to http://www.congresswest.com.au/dohad/

November 2007, Adelaide
Women's Hospitals Australasia & Children's Hospitals Australasia
November 12 – 16

'Responding with Style to Changes in Lifestyle'
Women's Hospitals Australasia & Children's Hospitals Australasia hold a joint conference each year at a different location in Australia and New Zealand. We welcome attendance from health professionals, health service managers, academics and others involved or interested in the health and welfare of women, children and babies.

For further programme information and registration details:
http://www.wcha.asn.au/index.cfm/spid/1_27.cfm 

November 2007, Sydney
Society of Obstetric Medicine of Australia and New Zealand (SOMANZ)
Clinical Refresher and Annual Scientific Meeting, Manly Pacific, Sydney
November 16-18

For further programme information and registration details: www.somanz.org

Festschrift for Professor David Henderson-Smart OAM, University of Sydney
November 22
Symposium 9am – 5pm

Dinner 7 pm
Email: atupai@perinatal.usyd.edu.au


Future Dates For Your Diary:

2008
April, Gold Coast
Australian College Neonatal Nurses Association Inc Annual Conference
Sunday 20th April

“Nurturing Generation Z” will provide a forum for health professions to explore the challenges in providing optimal care for the new generation.
Call for abstracts for oral and poster presentations are now open.
Closing date for submission is Friday 2nd November 2007.

Abstract guidelines and conference details now available on ACNN website: www.acnn.org.au
Or download preliminary announcement


Perinatal Society of Australia and New Zealand Annual Congress
Celebrating 25 years: Reflections and Projections
Gold Coast Convention & Exhibition Centre
Queensland, Australia
20 – 23 April 2008


Abstract submissions now open!
Details & instructions regarding submission of abstracts, now available on the website: www.psanz.org.au
Deadline for submission: Friday 9 November 2007


Presentations:

WOMBAT Presentations :

The following papers/poster will be presented at the Clinical Trials Symposium in Sydney later this month.

Title: Journal citations do not adequately measure impact of clinical trials: a perinatal example

Philippa Middleton, Caroline Crowther

Poster: Developing online learning modalities for education about trial design and conduct using a community of practice model.

Tooher R for the WOMBAT Collaboration

WOMBAT Affiliated Presentations:

Title: CONSORT for Abstracts: guidance to improve the quality of reporting of randomized trials in conference and journal abstracts
Sally Hopewell, Mike Clarke (UK Cochrane Centre, UK), David Moher (Chalmers Research Group, Canada), Liz Wager (Sideview, UK), Philippa Middleton (The University of Adelaide, Australia), Doug Altman (Centre for Statistics in Medicine, UK), Ken Schulz (Family Health International, USA)


News:

ACTORDS
More good news! The ACTORDS two year follow-up results will be published this week in The New England Journal of Medicine.
N Engl J Med 2007; 357:1179-89

ACTR
ACTR are pleased to announce the launch of the updated Australian Clinical Trials Registry (ACTR) website www.actr.org.au  
The latest version of the website has several new features including:
Improved search function: The ACTR search function is now more specific and comprehensive and includes the option to search on specific fields as well as the ability to sort and print your search results.

New Consort Website:
http://www.consort-statement.org/


Trial Updates:

Trials requiring more centres & more recruits

PPROMT Trial: Preterm Pre-Labour Rupture of Membranes Close to Term Trial
Should you like more information on becoming involved in this trial: email ppromt@med.usyd.edu.au


PROGRESS Trial: Progesterone after previous preterm birth for the prevention of neonatal respiratory distress syndrome
Should you like more information on becoming involved in this trial: email progress@adelaide.edu.au


New Publications:

1. Austin M-P, Frilingos M, Lumley J, Hadzi-Pavlovic D, Roncolato W, Acland S, Saint K, Segal N, Parker G. Brief antenatal cognitive behaviour therapy group intervention for the prevention of postnatal depression and anxiety: a randomised controlled trial. Journal of Affective Disorders 2007 epub ahead of print

2. Doyle LW, Davis PG, Morley CJ, McPhee A, Carlin JB DART Study Investigators. Outcome at 2 years of age of infants from the DART study: a multicenter, international, randomized, controlled trial of low-dose dexamethasone. Pediatrics 2007;119(4):716-21

3. Ghanta S, Abdel-Latif ME, Lui K, Ravindranathan H, Awad J, Oei J. Propofol compared with the morphine, atropine and suxamethonium regimen as inducuton agents for neonatal endotracheal intubation: a randomized, controlled trial. Pediatrics 2007;119(6):e1248-55.

4. Hennessy A, Thornton CE, Makris A, Ogle RF, Henderson-Smart DJ, Gillin AG, Child A. A randomised comparison of hydrazaline and mini-bolus diazoxide for hypertensive emergencies in pregnancy: the PIVOT trial. Australian and New Zealand Journal of Obstetrics and Gynaecology 2007;47:279-85

5. Whittle M. Does fetal bladder drainage have a role? PLUTO - a trial long overdue. British Journal of Obstetrics and Gynaecology 2007;114:794-5.


New Trials:

Beating the blues before birth: Evaluating an Antenatal Depression Treatment Model as a Public Health Priority
ACTR12607000397415
Currently recruiting
Victoria


Tips on Trials - Randomisation Services:

Randomisation services in Australia
Randomisation services in Australia: a snapshot of current and future support for maternal and perinatal trials

A number of organisations around Australia offer randomisation services for maternal and perinatal randomised clinical trials. Some services are limited to researchers within their own hospital, whilst others offer external national and international support for trials.

Determining the cost of establishing and maintaining a randomisation service is complicated. Chris Brown, a Biostatistician at the NHMRC Clinical Trials Centre (CTC) explained, “With so many variables involved in trials (and their randomisation) it is not possible to set a standard fee - our quotes depend on aspects of the trial such as: the sample size of the study, number of sites/users, frequency of randomisation, type of system (operator/IVR/web-based), method of randomisation (simple/blocks/minimisation), any kit/drug management requirements, site management requirements, use of toll free access, fax confirmations and other reporting options, etc. The cost of the systems depends on all these factors and varies accordingly.”

Boost II and the COSMOS trial use the NHMRC CTC randomisation service. Some of the COSMOS investigators had used telephone activated randomisation in previous trials and found it worked really well when recruiting in busy clinical areas. They have decided to use telephone activated randomisation (IVRS) for the COSMOS study. Internet randomisation was an alternative, but internet access was uncertain at some times and sites.

Download a copy of the full document
 


Call For Abstracts:

Abstract submissions are now open for:

The Australian College of Neonatal Nurses Inc (ACNN): visit www.acnn.org.au for submission guidelines.

Deadline: Friday 2 November 2007

PSANZ: visit www.psanz.org.au for submission instructions.

Deadline: Friday 9 November 2007


Further Information

For more information on WOMBAT initiatives, please contact the WOMBAT Collaboration national co-ordinator: p.middleton@WOMBATcollaboration.net

The WOMBAT Collaboration is funded through a NHMRC enabling grant